NASA must devise a strategy to return Apollo 13 to Earth safely after the spacecraft undergoes massive internal damage putting the lives of the three astronauts on board in jeopardy.

The screenplay by William Broyles Jr. and Al Reinert dramatizes the aborted 1970 Apollo 13 lunar mission and is an adaptation of the 1994 book Lost Moon: The Perilous Voyage of Apollo 13, by astronaut Jim Lovell and Jeffrey Kluger. The film depicts astronauts Lovell, Jack Swigert, and Fred Haise aboard Apollo 13 for America's fifth crewed mission to the Moon, which was intended to be the third to land. En route, an on-board explosion deprives their spacecraft of much of its oxygen supply and electrical power, which forces NASA's flight controllers to abort the Moon landing mission and improvise scientific and mechanical solutions to get the three astronauts to Earth safely.

Howard went to great lengths to create a technically accurate movie, employing NASA's assistance in astronaut and flight-controller training for his cast and obtaining permission to film scenes aboard a reduced-gravity aircraft for realistic depiction of the weightlessness experienced by the astronauts in space.

Released to cinemas in the United States on June 30, 1995, Apollo 13 received critical acclaim and was nominated for nine Academy Awards, including Best Picture (winning for Best Film Editing and Best Sound). The film also won the Screen Actors Guild Award for Outstanding Performance by a Cast in a Motion Picture, as well as two British Academy Film Awards.